Health Newsletter:June 2008
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[edit] Puzzling New Neurological Syndrome Investigated
A new neurological syndrome has been described in early December 2007 and is presenting a challenge not only to the affected patients but also to the health professionals. The illness is characterized by pain, sensory symptoms, weakness and fatigue. Abnormal lab tests and MRI scan results were also present. The syndrome has affected at east two dozen workers who are working in pig slaughterhouses in three states of the U.S. Researchers have now a somewhat clearer picture of the mysterious illness, but Dr. Daniel Lachance, assistant professor of neurology at the Mayo Clinic in Rochester, Minnesota, describes the illness as one of the kind that has “defied explanation and a name”. At this point investigators have called it “progressive inflammatory neuropathy” (PIN), but the term is merely descriptive but not accurate enough.Dr. Lachance described the clinical picture based on findings on 18 patients from Minnesota who have been investigated in the most comprehensive manner. The course of their illness was marked by pain, decreased sensation and tingling along with weakness and fatigue which far exceeded the findings of physical examinations. All of the affected individuals had abnormal MRI’s and abnormal results of the labs of their cerebrospinal fluid. Various tests of reflexes or quantitative sensory testing also showed abnormalities, and nerve conduction studies were abnormal in most of the patients. All of them had a new IgG auto-antibody biomarker. The findings point to an immune-mediated phenomenon which translates into a neurological illness. The workers affected all were exposed to aerosolized brain particles from slaughtered pigs. All workers worked in the “warm room” where pigs were slaughtered and the brain extracted in a technique in which compressed air is shot into a dead pig’s foramen magnum. This blast of compressed air not only emulsifies the brain, but some of it becomes aerosolized and airborne. Symptoms seem to start within days or weeks of exposure, after which the course of the disease is chronic. Treatment has been symptomatic in those most severely affected with the medications of choice being methylprednisolone and/or intravenous treatment with immune globulin. Researchers have tested early on for human and porcine pathogens, but no infectious agent has been found. The precise mechanism by which the illness is occurring is not fully understood, but the syndrome does not seem to be food borne or transmissible from person to person.
The Medical Post, May 13, 2008, page 14, 15.
[edit] New Modified Carrots and Food from Cloned Animals
Researchers from Texas A&M AgriLife’s Vegetable and Fruit improvement Center and a research group from Baylor College of Medicine reported about their work earlier this year. They developed a new variety of super carrots that contain 41% more calcium than the regular garden varieties. In a study 15 men and 15 women ate regular carrots for a week. At the end of the week urine samples were taken to examine the amount of calcium absorbed. The test persons ate the modified carrots for a week, and more urine tests were taken. The result showed a higher intake of calcium from the modified carrots. The head of the study, Dr. Jay Morris, PhD made a statement that fruit and vegetables are beneficial for many reasons, but they have never been a good food source for calcium. He states that if the new technology is applied to a number of different fruit and vegetables, it could have a significant impact on preventing osteoporosis. This research may sound like a futuristic concept, but bioengineering and food from bioengineered animals may soon be a reality for consumers in the United States and in Europe. The FDA has reported that, for the most part, milk and meat from cloned animals is safe to eat. The European Food Safety Authority has also concluded at the same time that milk and meat from healthy cloned cattle and pigs are suitable for human consumption. At this point there was not enough information for the agency to come to a conclusion on the safety of food from other animal clones, such as sheep. The European agency noted that death and disease rates are higher in cloned as compared to conventionally reproduced animals, and it would be of essence that unhealthy clones will not enter the food supply. The European Group on Ethics in Science and New Technologies (EGE) advises against food production from cloned animals due to the current level of suffering and health problems in surrogate dams and animal clones. Cloning remains fraught with perinatal and postnatal disease of cloned animals. Abnormalities are also common in the form of malformations, increased weight, respiratory problems, enlarged fetal liver and kidney abnormalities. Ultimately the old adage is as valid as ever, even if it comes to the mundane task of shopping for dinner. It is called “buyer beware”!
The Medical Post, April 22, 2008, page 25
[edit] You Are What You Sleep
Stressful lifestyles often contribute to physical disorders and psychological difficulties, but little has been known about the fact that unbalanced sleep patterns also dysbalance a healthy body weight. Jean –Philippe Chaput of Laval University, Quebec City presented some facts at the 16 th European Congress on Obesity in Geneva, that emphasizes the importance of a balanced sleep pattern. There can be not only too little sleep but also too much sleep, as Dr. Chaput found out by studying 276 adults. Those who had a pattern of short duration sleep(5 to 6 hours) and those individuals who slept 9 to 10 hours were 35% and 25% more likely, respectively to show weight gains of 5 kg compared to the group that slept for 7 to 8 hours. The most likely reason is an alteration of certain hormones: short sleepers had high leptin levels and low ghrelin levels. In a previous study on children it also became obvious that to little sleep increases the risk of overweigh and obesity in children. It was also possible to establish the type of weight gain. Short sleep duration in kids lead to abdominal fat rather than to overall body fat deposits. Too little sleep in children seems to have more health consequences than previously thought, as it is the most important risk factor for overweight in this group. Only after the risk of sleep duration that is too short rank parental obesity, watching TV and lack of physical activity.
From the 16th European Congress on Obesity, May 2008
[edit] Boost Babies’ Health with Mom’s Diet
Prenatal supplements and good advice on proper nutrition during pregnancy have long been included in proper prenatal care. Importance has been placed on folic acid to prevent neural tube defects in the fetal development. Calcium is recommended, often in the form of dairy products, but it does not end there: just swallowing the supplement and adding some more milk may be helpful but not quite enough. Certain dietary habits have been found more beneficial, such as the eating habits in the Mediterranean countries. A research team from the University of Crete in Heraclion, Greece included women who were involved in antenatal care at all general practices in Menorca, Spain. The study took place in the time frame of 12 month starting in 1997. After six and a half years 460 children were also included in the analysis. Dietary habits were studied and assessed by food questionnaires and the children were assessed for the development of allergy and asthma. The children of mothers who consumed the most vegetables, fish and legumes were almost 80% less likely to have persistent wheeze and more than 40 % less likely to have allergies. The results are consistent with the fact that a high level of adherence to the Mediterranean diet during pregnancy is protective not only to the mother but also to the child.
The Medical Post, April 22, 2008, page 25
[edit] Diabetes Onset Can be Delayed
Prevention is the buzzword in healthcare, but often medicine has to embark on the curative avenues. With the onset of a health problem patients are often tempted to throw in the towel: it’s too late now anyways. I there is nothing I can do. It’s up to medication, pills or shots to get a handle on my problem. Nothing could be further from the truth, as major clinical trials have shown, when it comes to intervention to prevent the onset of diabetes. There is a stage where lab tests show that a patient has impaired glucose tolerance. He or she is”pre-diabetic”. Without intervention the development of diabetes is more or less imminent. But this does not mean that “it is not too late “.It is exactly the point, where lifestyle intervention can make a difference. How long do these post-intervention studies remain effective? Professor Guangwei Li at the China-Japan Friendship Hospital in Beijing, China and Dr. Ping Zhang from Centers for Disease Control and Prevention followed up patients 20 years after enrolment. In 1986, 577 adults from 33 clinics in China were randomly assigned to a control group or one of three lifestyle intervention groups( diet, exercise or diet and exercise combined).All of the patients had impaired glucose tolerance. There was an active intervention program until 1992, and in 2006 participants were assessed for the long-term effect of the interventions. The results showed that the combined lifestyle interventions reduced the incidence of diabetes by about half during the active intervention period of 6 years. Over the 20 year duration the reduction was 43 %. At the end of the 20 year period 80% of the intervention group had developed diabetes, whereas 93% of the control group that had not followed a lifestyle intervention program were diabetic. The researchers reported that lifestyle intervention programs for patients with impaired glucose tolerance can indeed make a difference. A six year intervention program can delay the onset of diabetes by 14 years.
Lancet 2008;371:1783-1789; 1731-1733.
