Crohns Disease Symptoms

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[edit] Crohns Disease Symptoms

The cardinal symptoms for Crohns disease are chronic diarrhea, abdominal pain and fever. The diarrhea is mostly bloody, but is absent in 15 to 25% of cases. There is often pain in the pain right lower abdomen, which has to be delineated from other causes of abdominal pain such as appendicitis, ectopic pregnancy (tubal pregnancy) in women etc. About 25 to 30% have either a history or else have active perianal fistulas or ulcers.

When this occurs, it is a powerful pointer to Crohns disease. Histologically these perianal fistulas are the same granulomatous tissue as Crohns lesions inside the bowel wall. Other symptoms are associated with malabsorption syndrome or are due to other associated conditions that often are found alongside Crohns disease.

For instance, Crohns disease anemia and growth retardation are due to malabsorption. The same is true for the higher incidence of kidney stones (change in metabolism of uric acid and increased absorption of oxalate) and gall stones (impaired absorption of bile salts).

However, symptoms of lower back pain and arthritic type joint pains point to a known association with ankylosing spondylitis. This inherited connective tissue disease is associated with a certain histocompatibility antigen (HLA antigen B27).

With chronic Crohns disease there is weight loss due to malabsorption. The scarring of the affected bowel area and internal fistula formations lead to more and more presentations to the surgeon and occasional surgeries will have to be done. The surgeon will like to avoid surgery as it is common knowledge that these patients do not heal well and will likely have new recurrences of fistulas and bowel obstructions with more and more difficult decisions in future how to handle this.

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