Child – ALL

What is acute lymphoblastic leukemia (ALL) in children?

ALL is the type of leukemia that accounts for the majority of childhood leukemia cases.

What are the signs and symptoms of ALL in children?

Signs and symptoms of ALL relate to the presence of anemia caused by a high number of white blood cells and low number of red blood cells in the body. The signs and symptoms include:
• Pale skin;
• Weakness;
• Laziness;
• Poor appetite;
• Weight loss;
• Bleeding from minor bruises;
• Pin size blood spots (petechiae);
• Blood blisters often on lower legs (purpura);
• Frequent infections;
• Liver enlargement; and
• Bone pain – can cause limp or walking problem.

How is ALL diagnosed?

Diagnosis involves the use of leukemia blood tests, a bone marrow aspirate and/or a bone marrow biopsy. Lung X-rays and a CT or MRI brain scan are often used to rule out involvement of the lungs and brain.

How is ALL treated?

In preparation for chemotherapy, the physician will assess the function of liver and kidney using special blood tests. Treatment is performed based on which of the following phases the patient is in:

Remission induction aims to stop the ALL from multiplying and to get it under control. Drugs such as prednisone and vincristine are the traditional drugs used. This form of chemotherapy induces a remission of approximately four weeks.

Prevention – This step involves restricting the leukemia from spreading through the central nervous system. It involves a combination of triple chemotherapy (hydrocortisone, cytarabine, and methotrexate).

Consolidation and maintenance therapy has been introduced to extend the period of time before a patient relapses. from Two chemotherapeutic agents are given daily or weekly. The treatment may end after two and a half or three years.

Relapse occurs when the leukemia returns despite the cheap nfl jerseys initial chemotherapy treatment. Initial symptoms of leukemia occur which prompt the physician to perform blood tests. If the leukemia has returned, a quadruple chemotherapeutic drug regimen is used.

A bone marrow transplant may be employed to treat difficult cases of ALL. They are performed using compatible bone jordan retro 1 marrow cells from a donor.

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