Systemic Lupus Erythematosus

Introduction

Lupus (or “systemic lupus erythematosus” how it is medically termed) is a rheumatic illness that is relatively rare. There are about 30 cases of lupus among 100,000 black people, particularly Afro-Americans. Lupus is about 3 to 4 fold more frequent among them when compared to whites. Women are affected 9-fold more frequently than men (Ref.1). It is a disease with many cheap nba jerseys different manifestations. And it cheap nfl jerseys is related to other autoimmune diseases with which there is an overlap: rheumatoid arthritis, scleroderma, polymyositis, Sj√∂gren’s syndrome and Neuer dermatomyositis.

In some patients it affects the skin more cheap ray bans (lupus rash), in others the joints and in the more severe cases it is a systemic disease affecting several internal organs. Recent research has established that lupus is genetically determined through several loci. There is at least one locus that controls susceptibility to lupus. There is at least one other locus that controls suppression of lupus and if it is missing the carrier of this gene defect is much more susceptible to lupus discount football jerseys (Ref. 3).

Summary

Lupus is a multifaceted disease that has some genetic predisposition that needs to be triggered. Diagnostic efforts need to rule out secondary lupus as a reaction to drugs and other rheumatological conditions (about 5 other possibilities) need to be ruled out. When the diagnosis is confirmed, treatment should be supervised by a rheumatologist to ensure that aggressive therapy is warranted. Sometimes watchful observation might be the wiser thing to do. Care has to be taken not to overuse corticosteroids or immunosuppressive agents as the course discount oakley of most lupus cases is relatively benign compared to the potentially deadly side effects of some of the therapeutic modalities.

This entry was posted by admin on Friday, April 2nd, 2010 at 8:00 am and is filed under Uncategorized . You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.